I’ve spent years fine-tuning my supplement stack, testing combinations that promise more energy, cleaner metabolism, better digestion, and sustainable health. Out of all the variations I’ve tried, one specific trio keeps rising to the top: TMG, Berberine, and Volcanic Pink Salt. These three work synergistically in ways most people overlook, especially when the goal isn’t just performance—but cellular-level detox and renewal.
This isn’t about hype or hacks. It’s about understanding what your body truly needs to stay clean, resilient, and optimized.
Let’s talk about why I’ve chosen this trio—and why I use it every single day.
What Detox Really Means to Me
Most people hear the word “detox” and think about juice cleanses or fasting. But for me, detoxification is about supporting the body’s natural systems: liver, kidneys, cellular methylation, and gut lining integrity. Real detox isn’t flashy—it’s consistent. It’s what you do daily to clear out the metabolic waste, environmental toxins, and oxidative stress that build up quietly but steadily over time.
That’s where this stack comes in.
TMG: The Methylation Catalyst
Trimethylglycine, or TMG, is one of those supplements I didn’t fully appreciate until I understood methylation. This biochemical process is how your body turns off harmful genes, repairs DNA, and eliminates toxins. It’s foundational to everything from cardiovascular health to brain function.
TMG gives your body the methyl groups it needs to complete those detox cycles efficiently—especially when it comes to clearing homocysteine, which can build up and damage your blood vessels if left unchecked.
Since I started taking TMG regularly, I’ve felt a noticeable improvement in mental clarity and resilience during stressful weeks. And the science backs it. In fact, I break it down fully in What Is TMG and How Does It Benefit Your Health if you want a full primer.
Berberine: The Gut-Guardian and Metabolic Modulator
There’s a reason I consider Berberine Plus a flagship of our supplement line. Berberine is not only powerful for balancing blood sugar and cholesterol—it also acts like a natural antimicrobial in the gut. That matters more than you might think.
Your gut is where detox really begins. If your microbiome is off, or if your intestinal lining is compromised, toxins start slipping through. That’s why I use berberine not just for metabolism, but to maintain gut integrity—keeping harmful bacteria in check and ensuring the nutrients I take are actually absorbed.
Volcanic Pink Salt: The Forgotten Foundation of Detox
I saved this one for last because most people completely overlook it. Hydration and mineral balance are foundational to detox—and nothing restores that balance like Volcanic Pink Salt. It’s not just sodium—it’s magnesium, calcium, potassium, and trace minerals your body craves for cellular function.
If your cells are dehydrated or mineral-depleted, your detox pathways slow down. Toxins linger. Energy drops. That’s why I add a pinch of this salt to my water first thing in the morning. It’s not a gimmick—it’s how I prime my system to flush out what doesn’t belong.
Why These Three Together?
I’ve tried detox protocols that cost hundreds of dollars and overcomplicate everything. What I’ve learned is this: when you support methylation with TMG, gut health with berberine, and mineral hydration with volcanic pink salt, the rest tends to follow. You sleep better. You digest more cleanly. You think more clearly. You recover faster.
I detailed this strategy in The Ultimate Wellness Stack but this version—the detox-focused variation—is how I recalibrate when life gets chaotic or stress levels rise.
A Final Word on Stacking with Purpose
Supplements aren’t magic, but they can be powerful when used with intention. This stack is about clarity. Clean energy. Deep restoration. It’s not just for people chasing fat loss or muscle gain—it’s for those of us who want to function well into our later years, free from the noise of bloating, brain fog, and burnout.
So yes—I stack TMG, Berberine, and Volcanic Pink Salt daily. Not for some trendy detox goal. But because it works. And if you’ve tried everything else and still feel off? This might just be the stack that shifts things for you.
—Doug Krussel
Founder, K3 Nutriments